I've had success with Sysinternals Process Explorer. With this, you can search to find what process(es) have a file open, and you can use it to close the handle(s) if you want. Of course, it is safer to close the whole process. Exercise caution and judgement.
To find a specific file, use the menu option "Find->Find Handle or DLL..." Type in part of the path to the file. The list of processes will appear below.
edited Dec 31 '12 at 17:46
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answered May 1 '09 at 1:03
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